Changes between Version 1 and Version 2 of WhatCanVespa_Do


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Timestamp:
Dec 14, 2012, 8:49:31 AM (7 years ago)
Author:
bsoher
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  • WhatCanVespa_Do

    v1 v2  
    1 = What Can VeSPA Do for Me? =
     1= What Can Vespa Do for Me? =
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    3 Listed below are some of the ways to use VeSPA, both by taking advantage of the updated and extended capabilities of the individual packages, and working with the combined and integrated toolset.
     3Listed below are some of the ways to use Vespa, both by taking advantage of the updated and extended capabilities of the individual packages, and working with the combined and integrated toolset.
    44
    55=== Individual Packages ===
     
    5151=== Integrated Toolset ===
    5252
    53 As an integrated toolset, VeSPA can be even more powerful that it's component parts. One typical use of the integrated package will be to iteratively design a RF pulse and test it's effect on the spectra of metabolites of interest. Details of the method for providing the pulses generated by RFpulse to the sequence design methods used by Simulation are under development, but a tutorial linked to below shows how to read a text file containing a list of real and imaginary values representing a pulse, into pygamma code for a simulation. Once you are satisfied with the resulting pulse and pulse sequence design, an experiment could be run and fit using the Analysis package and the Simulation results.
     53As an integrated toolset, Vespa can be even more powerful that it's component parts. One typical use of the integrated package will be to iteratively design a RF pulse and test it's effect on the spectra of metabolites of interest. Details of the method for providing the pulses generated by RFpulse to the sequence design methods used by Simulation are under development, but a tutorial linked to below shows how to read a text file containing a list of real and imaginary values representing a pulse, into pygamma code for a simulation. Once you are satisfied with the resulting pulse and pulse sequence design, an experiment could be run and fit using the Analysis package and the Simulation results.
    5454
    5555In this scenario, results generated by the Simulation package are used by the Analysis package for spectral fitting. This is one of the two major methods currently in use for providing basis function for fitting MRS data. The other method is to apply the pulse sequence to be used in the experiment to phantoms containing the metabolites of interest (provided that the eventual application will be to a sample containing the set of metabolites such as a biological sample) and to use the resulting functions as "basis functions" for the fitting procedure. Both methods have strengths and weaknesses, and both can produce basis functions that can be used by the Analysis package but for a number of reasons the authors are advocates of the method of generating basis functions via spectral simulation.
    5656
    57 The VeSPA package is obviously and specifically designed to make use of spectral simulations, and the tutorials below focus on how to generate "basis functions" using the Simulation package.   
     57The Vespa package is obviously and specifically designed to make use of spectral simulations, and the tutorials below focus on how to generate "basis functions" using the Simulation package.